Furthermore, Itch/AIP4 has been proven to mediate polyubiquitylation-dependent targeting of retrovirally portrayed Notch1 ectodomain to lysosomes in the lack of ligand (Chastagner et al

Furthermore, Itch/AIP4 has been proven to mediate polyubiquitylation-dependent targeting of retrovirally portrayed Notch1 ectodomain to lysosomes in the lack of…

Analysis centered on 4 poor prognostic elements: visceral metastases, liver organ metastases (subset of visceral metastases), progesterone receptor-negative position and great tumor grade

Analysis centered on 4 poor prognostic elements: visceral metastases, liver organ metastases (subset of visceral metastases), progesterone receptor-negative position and…

The habitual use of anti-hypertensive medicines was investigated and questions on the use of diuretics (hydrochlorotiazides, furosemide, spironolactone), beta-blockers, angiotensin converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARBs), calcium channel antagonists (CCA), alpha-blockers, and clonidine were categorized as follows: no habitual consumption?=?0, habitual usage?=?1

The habitual use of anti-hypertensive medicines was investigated and questions on the use of diuretics (hydrochlorotiazides, furosemide, spironolactone), beta-blockers, angiotensin…

The intensity of sinus hypertrophy assessed by CT might predicts possibility of NERD, and sinus CT score below 12 would support the probability of aspirin tolerance within a patients with unclear history of hypersensitivity a reaction to aspirin and NSAIDs [48]

The intensity of sinus hypertrophy assessed by CT might predicts possibility of NERD, and sinus CT score below 12 would…

Therefore, the observed early responders to dupilumab treatment in severe asthma are concordant with both basic mechanisms and previously confirmed clinical effects on moderate-to-severe atopic dermatitis

Therefore, the observed early responders to dupilumab treatment in severe asthma are concordant with both basic mechanisms and previously confirmed…