Posted on


2019;8(11):2013. of acrosyndromes for antisynthetase syndrome. However, Herrick et al recently published recommendations on the management of connective tissue disease\related digital vasculopathy. 16 They are based on a nonpharmacological approach (avoiding cold, protecting extremities, stopping smoking) and a pharmacological approach, the latter depending on the presence of complications (digital ulceration and/or crucial ischemia). CONFLICT OF INTEREST None declared. AUTHOR CONTRIBUTION AT: initiated the manuscript preparation. All the authors: participated in the clinical management of this patient and contributed to the manuscript preparation. ETHICAL APPROVAL Local approbation, patient consent. Notes Abrassart T, Roland T, Laurent F, Rossi C. A case of antisynthetase syndrome with chilblains\like lesions and microangiopathy. Clin Case Rep. 2021;9:1446C1449. 10.1002/ccr3.3790 [CrossRef] [Google Scholar] First author: Tom Abrassart. DATA AVAILABILITY Available upon submission. Recommendations 1. Seve P, Lega J\C, Broussolle C, Rousset H. Diagnostics difficiles en mdecine interne: vol. 2. Paris: Maloine; 2018. [Google Scholar] 2. Witt L, Curran J, Strek M. The diagnosis and treatment of antisynthestase syndrome. Clin Pulm Med. 2016;23(5):218\226. [PMC free article] [PubMed] [Google Scholar] 3. Cavagna L, Trallero\Araguas E, Meloni F, et al. Influence of antisynthetase antibodies specificities on antisynthetase syndrome clinical spectrum time course. J Clin Med. 2019;8(11):2013. [PMC free article] K+ Channel inhibitor [PubMed] [Google Scholar] 4. Hervier B, Devilliers H, Stanciu R, et al. Hierarchical cluster and survival analyses of antisynthetase syndrome : phenotype and outcome are correlated with anti\tRNA synthetase antibody specificity. Autoimmun Rev. 2012;12(2):210\217. [PubMed] [Google Scholar] 5. Sebastiani M, Triantafyllias K, Manfredi A, et al. Nailfold capillaroscopy characteristics of anti\synthetase syndrome and possible clinical associations: results of a multicenter international study. J Rheumatol. Rabbit Polyclonal to RAD21 2019;46(3):279\284. [PubMed] [Google Scholar] 6. Satoh M, Tanaka S, Ceribelli A, Calise SJ, Chan EK. A comprehensive overview on myositis\specific K+ Channel inhibitor antibodies: new and aged biomarkers in idiopathic inflammatory myopathy. Clin Rev Allergy Immunol. 2017;52(1):1\19. [PMC free article] [PubMed] [Google Scholar] 7. Baccaro A, Berhens Pinto G, Carboni R, Shinjo S. The clinical manifestations at the onset of antisynthetase syndrome: a chameleon with multiples faces. Reumatismo. 2020;72(2):86\92. [PubMed] [Google Scholar] 8. Mariampillai K, Granger B, Amelin D, et al. K+ Channel inhibitor Development of a new classification system for idiopathic inflammatory myopathies based on clinical manifestations and myositis\specific autoantibodies. JAMA Neurol. 2018;75(12):1528\1537. [PMC free article] [PubMed] [Google Scholar] 9. De Greef A, Marot L, Yildiz H, Baeck M. Dermatomyositis with anti\TIF1\ antibodies. Case Reports. 2018;2018:bcr\2018\227574. [PMC free article] [PubMed] [Google Scholar] 10. Jubber A, Tripathi M, Taylor J. Interstitial lung disease and inflammatory myopathy in antisynthetase syndrome with PL\12 antibody. Case Reports. 2018;2018:bcr\2018\226119. [PMC free article] [PubMed] [Google Scholar] 11. Usman Khan M, McCormick D. 14.?Digital ischemia and interstitial lung disease in antisynthetase syndrome with PL\12 antibody. Rheumatol Adv Pract. 2019;3(Supplement_1). 10.1093/rap/rkz030.013. [CrossRef] [Google Scholar] 12. Mertz P, Herber M, Jeannel J, Korganow AS, Guffroy A. Persistent acrocyanosis\a rare manifestation revealing anti\PL\12 syndrome. Arthritis Rheumatol. 2018;70(10):1698. [PubMed] [Google Scholar] 13. Belch J, Carlizza A, Carpentier PH, et al. ESVM guidelines \ the diagnosis and management of Raynaud’s phenomenon. Vasa. 2017;46(6):413\423. [PubMed] [Google Scholar] 14. Das S, Maiti A. Acrocyanosis: an overview. Indian J Dermatol. 2013;58(6):417\420. [PMC free article] [PubMed] [Google Scholar] 15. Chatelanat O, Ven Delden C, Adler D, Guerne PA, Nendaz M, Serratrice J. Facteurs de risque et prophylaxie de la pneumonie chez les patients non VIH. Rev Med Suisse. 2018;14:18\22. [PubMed] [Google Scholar] 16. Herrick A, Wigley F. Raynauds phenomenon. Best Pract Res Clin Rheumatol. 2020;34(1):101474. [PubMed] [Google Scholar].