Indeed, while SAC genes are frequently mutated in various solid tumors including colon, breast, prostate and lung [66,67,68,69,70,71,72], a survey of four MB datasets included in the cBioPortal [4,73,74,75] revealed a lower-than-expected mutation rate in BUB1, BUB1B, BUB3, MAD1L1, MAD2L1, CDC20 (the maximal rate of inactivating mutations was 0

Indeed, while SAC genes are frequently mutated in various solid tumors including colon, breast, prostate and lung [66,67,68,69,70,71,72], a survey…